Long COVID –Visual hallucinations

Visual hallucinations (HP:0002367)

Visual perceptions that are not elicited by a corresponding stimulus from the outside world.

Synonyms:    Visual hallucinations

Cross References:    MSH:D006212, SNOMEDCT_US:64269007, UMLS:C0233763

KEGG Pathway

IndexNameP-valueAdjusted p-valueOdds RatioCombined score
1Inositol phosphate metabolism0.032380.144934.58118.62
2ECM-receptor interaction0.038920.144928.6092.84
3Spinocerebellar ataxia0.062550.144917.4748.43
4mTOR signaling pathway0.067220.144916.2143.76
5Protein processing in endoplasmic reticulum0.074380.144914.5737.87

GO: Biological Process

IndexNameP-valueAdjusted p-valueOdds RatioCombined score
1positive regulation of AMPA receptor activity (GO:2000969)0.0022480.03359624.593808.55
2reelin-mediated signaling pathway (GO:0038026)0.0022480.03359624.593808.55
3cerebral cortex cell migration (GO:0021795)0.0026970.03359499.652955.69
4regulation of oxidative stress-induced neuron death (GO:1903203)0.0035950.03359356.862008.48
5TORC1 signaling (GO:0038202)0.0035950.03359356.862008.48

GO: Molecular Function

IndexNameP-valueAdjusted p-valueOdds RatioCombined score
1cuprous ion binding (GO:1903136)0.0035950.02845356.862008.48
2phospholipase inhibitor activity (GO:0004859)0.0044920.02845277.531500.17
3lipase inhibitor activity (GO:0055102)0.0044920.02845277.531500.17
4lipoprotein particle receptor binding (GO:0070325)0.012530.0595392.43404.78
5copper ion binding (GO:0005507)0.020070.0762856.67221.48

GO: Cellular Component

IndexNameP-valueAdjusted p-valueOdds RatioCombined score
1Lewy body (GO:0097413)0.0022480.03595624.593808.55
2clathrin-sculpted gamma-aminobutyric acid transport vesicle (GO:0061200)0.0035950.03595356.862008.48
3clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane (GO:0061202)0.0035950.03595356.862008.48
4SCF ubiquitin ligase complex (GO:0019005)0.025800.0754843.71159.87
5azurophil granule membrane (GO:0035577)0.025800.0754843.71159.87

Hub genes predicted as biomarkers & predicted FDA approved drugs

Hub Genes (ranked)FDA-Approved Drugs
DNAJC5
FBXO7
GIGYF2
SNCB
NPRL3
FIG4
LGI1
RELN
EPM2A