Abnormal pancreas morphology (HP:0012090)
Synonyms: Abnormally shaped pancreas, Abnormality of pancreas morphology
Cross References: UMLS:C4023049
GO: Biological Process
| Index | Name | P-value | Adjusted p-value | Odds Ratio | Combined score |
| 1 | cilium assembly (GO:0060271) | 7.884e-19 | 4.178e-17 | 196860.00 | 8205971.98 |
| 2 | ciliary basal body-plasma membrane docking (GO:0097711) | 8.554e-18 | 2.267e-16 | 915.08 | 35962.78 |
| 3 | cilium organization (GO:0044782) | 2.747e-17 | 4.853e-16 | 812.51 | 30983.64 |
| 4 | plasma membrane bounded cell projection assembly (GO:0120031) | 1.681e-16 | 2.227e-15 | 659.81 | 23965.68 |
| 5 | smoothened signaling pathway (GO:0007224) | 3.049e-12 | 2.693e-11 | 665.33 | 17642.09 |
GO: Molecular Function
| Index | Name | P-value | Adjusted p-value | Odds Ratio | Combined score |
| 1 | gamma-tubulin binding (GO:0043015) | 0.01144 | 0.02289 | 100.85 | 450.83 |
| 2 | tubulin binding (GO:0015631) | 0.1433 | 0.1433 | 7.15 | 13.88 |
GO: Cellular Component
| Index | Name | P-value | Adjusted p-value | Odds Ratio | Combined score |
| 1 | ciliary membrane (GO:0060170) | 4.016e-7 | 0.000001406 | 305.54 | 4499.94 |
| 2 | cilium (GO:0005929) | 5.245e-10 | 3.672e-9 | 128.31 | 2741.69 |
| 3 | cell projection membrane (GO:0031253) | 0.00001104 | 0.00002576 | 95.83 | 1093.80 |
| 4 | bounding membrane of organelle (GO:0098588) | 0.005508 | 0.009639 | 10.78 | 56.10 |
| 5 | cell-cell junction (GO:0005911) | 0.1276 | 0.1786 | 8.12 | 16.71 |
Hub genes predicted as biomarkers & predicted FDA approved drugs
| Hub Genes (ranked) | FDA-Approved Drugs |
| RPGRIP1L | – |
| TMEM216 | – |
| MKS1 | – |
| TCTN2 | – |
| TCTN3 | – |
| CC2D2A | – |
| B9D2 | – |
| B9D1 | – |
| TMEM231 | – |
| NPHP3 | – |
