Autoimmunity- Anti-thyroid peroxidase antibody positivity
May 23, 2022HPO Term: Anti-thyroid peroxidase antibody positivity (HP:0025379)
Definition: The presence of autoantibodies (immunoglobulins) in the serum that react against thyroid peroxidase.
Plain-language label: Anti-thyroid peroxidase antibody
Plain-language definition: An autoantibody is a kind of antibody that is directed against a substance made by one’s own body (usually, antibodies are directed against external agents such as bacteria). This term refers to an autoantibody directed against the protein thyroid peroxidase.
Gene-Association
Hub genes & Drug repurposing
RASGRP1 | – |
HRAS | – |
KRAS | PANITUMUMAB, CETUXIMAB |
NRAS | BINIMETINIB |
RAP1B | – |
RAP1A | – |
PLCG1 | CEFIXIME, DICLOFENAC |
PRKCQ | – |
SKAP1 | – |
DGKZ | – |