Autoimmunity- Anti-thyroid peroxidase antibody positivity

May 23, 2022 Off By admin

HPO Term: Anti-thyroid peroxidase antibody positivity (HP:0025379)

Definition: The presence of autoantibodies (immunoglobulins) in the serum that react against thyroid peroxidase.

Plain-language label: Anti-thyroid peroxidase antibody
Plain-language definition: An autoantibody is a kind of antibody that is directed against a substance made by one’s own body (usually, antibodies are directed against external agents such as bacteria). This term refers to an autoantibody directed against the protein thyroid peroxidase.

Gene-Association

GO

KEGG Pathway

Hub genes & Drug repurposing

RASGRP1
HRAS
KRASPANITUMUMAB, CETUXIMAB
NRASBINIMETINIB
RAP1B
RAP1A
PLCG1CEFIXIME, DICLOFENAC
PRKCQ
SKAP1
DGKZ