Autoimmunity- Anti-thyroid peroxidase antibody positivity
May 23, 2022HPO Term: Anti-thyroid peroxidase antibody positivity (HP:0025379)
Definition: The presence of autoantibodies (immunoglobulins) in the serum that react against thyroid peroxidase.
Plain-language label: Anti-thyroid peroxidase antibody
Plain-language definition: An autoantibody is a kind of antibody that is directed against a substance made by one’s own body (usually, antibodies are directed against external agents such as bacteria). This term refers to an autoantibody directed against the protein thyroid peroxidase.
Gene-Association
Hub genes & Drug repurposing
| RASGRP1 | – |
| HRAS | – |
| KRAS | PANITUMUMAB, CETUXIMAB |
| NRAS | BINIMETINIB |
| RAP1B | – |
| RAP1A | – |
| PLCG1 | CEFIXIME, DICLOFENAC |
| PRKCQ | – |
| SKAP1 | – |
| DGKZ | – |


