Antinuclear antibody positivity -KEGG Pathway

May 19, 2022 Off By admin

Antinuclear antibody positivity (HP:0003493)

KEGG Pathway

Index	Name	P-value	Adjusted p-value	Odds Ratio	Combined score
1	Autoimmune thyroid disease	0.000002081	0.00006243	170.91	2236.02
2	Riboflavin metabolism	0.003994	0.008875	317.19	1751.86
3	Measles	4.542e-7	0.00002725	98.05	1431.99
4	African trypanosomiasis	0.0001485	0.0007952	142.54	1256.48
5	Allograft rejection	0.0001567	0.0007952	138.57	1214.06
6	Graft-versus-host disease	0.0001917	0.0008613	124.69	1067.29
7	Type I diabetes mellitus	0.0002010	0.0008613	121.64	1035.45
8	Apoptosis	0.00004054	0.0005679	61.21	618.98
9	Hepatitis C	0.00005469	0.0005679	55.20	541.75
10	Necroptosis	0.00005679	0.0005679	54.49	532.69
11	Cytokine-cytokine receptor interaction	0.000009081	0.0001816	45.13	523.92
12	Pathogenic Escherichia coli infection	0.0001073	0.0007952	43.73	399.69
13	Th1 and Th2 cell differentiation	0.0009195	0.003523	55.28	386.48
14	Rheumatoid arthritis	0.0009395	0.003523	54.67	381.04
15	Human immunodeficiency virus 1 infection	0.0001334	0.0007952	40.56	361.91
16	Hematopoietic cell lineage	0.001064	0.003754	51.27	351.00
17	Chagas disease	0.001128	0.003762	49.73	337.48
18	Human cytomegalovirus infection	0.0001590	0.0007952	38.16	333.78
19	Th17 cell differentiation	0.001241	0.003918	47.35	316.84
20	TNF signaling pathway	0.001358	0.004075	45.18	298.27
21	Osteoclast differentiation	0.001741	0.004975	39.73	252.41
22	Natural killer cell mediated cytotoxicity	0.001851	0.005048	38.49	242.18
23	Pathways in cancer	0.00009084	0.0007786	24.62	229.14
24	Non-alcoholic fatty liver disease	0.002578	0.006725	32.41	193.21
25	JAK-STAT signaling pathway	0.002812	0.006748	30.98	182.00
26	Hepatitis B	0.002812	0.006748	30.98	182.00
27	Influenza A	0.003162	0.007297	29.15	167.78
28	Epstein-Barr virus infection	0.004331	0.009221	24.74	134.62
29	Proteoglycans in cancer	0.004457	0.009221	24.37	131.91
30	Cytosolic DNA-sensing pathway	0.03106	0.05177	35.71	123.99
31	Lipid and atherosclerosis	0.004890	0.009781	23.21	123.50
32	Inflammatory bowel disease	0.03204	0.05195	34.59	119.03
33	RIG-I-like receptor signaling pathway	0.03446	0.05441	32.08	108.04
34	p53 signaling pathway	0.03591	0.05525	30.74	102.25
35	B cell receptor signaling pathway	0.03978	0.05967	27.65	89.16
36	MAPK signaling pathway	0.008965	0.01735	16.86	79.51
37	Staphylococcus aureus infection	0.04651	0.06628	23.52	72.16
38	Fc gamma R-mediated phagocytosis	0.04747	0.06628	23.03	70.18
39	Viral protein interaction with cytokine and cytokine receptor	0.04890	0.06628	22.32	67.37
40	Human papillomavirus infection	0.01126	0.02110	14.94	67.03
41	T cell receptor signaling pathway	0.05081	0.06628	21.45	63.92
42	Toll-like receptor signaling pathway	0.05081	0.06628	21.45	63.92
43	NF-kappa B signaling pathway	0.05081	0.06628	21.45	63.92
44	PI3K-Akt signaling pathway	0.01280	0.02327	13.95	60.79
45	Neurotrophin signaling pathway	0.05794	0.07397	18.71	53.30
46	Lysosome	0.06220	0.07775	17.38	48.27
47	FoxO signaling pathway	0.06362	0.07790	16.97	46.76
48	Cell adhesion molecules	0.07160	0.08592	15.00	39.55
49	Pathways of neurodegeneration	0.02233	0.03940	10.32	39.22
50	Phagosome	0.07347	0.08643	14.60	38.11
51	Herpes simplex virus 1 infection	0.02439	0.04182	9.83	36.49
52	Tuberculosis	0.08646	0.09840	12.30	30.10
53	NOD-like receptor signaling pathway	0.08692	0.09840	12.23	29.87
54	Kaposi sarcoma-associated herpesvirus infection	0.09244	0.1027	11.46	27.28
55	Human T-cell leukemia virus 1 infection	0.1043	0.1138	10.08	22.78
56	Ras signaling pathway	0.1102	0.1180	9.50	20.97
57	Shigellosis	0.1164	0.1211	8.95	19.26
58	Salmonella infection	0.1178	0.1211	8.84	18.92
59	Endocytosis	0.1191	0.1211	8.74	18.59
60	Alzheimer disease	0.1699	0.1699	5.92	10.50

Categoryautoimmunity

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