Anti-thyroid peroxidase antibody positivity-KEGG Pathway

May 23, 2022 Off By admin

Anti-thyroid peroxidase antibody positivity (HP:0025379)

KEGG Pathway

Index	Name	P-value	Adjusted p-value	Odds Ratio	Combined score
1	PD-L1 expression and PD-1 checkpoint pathway in cancer	1.354e-12	8.178e-11	359.77	9831.65
2	T cell receptor signaling pathway	3.526e-12	9.698e-11	304.47	8029.08
3	Long-term potentiation	9.011e-11	1.647e-9	321.42	7434.41
4	Renal cell carcinoma	1.048e-10	1.647e-9	311.34	7154.30
5	Neurotrophin signaling pathway	8.044e-12	1.770e-10	263.85	6740.44
6	Rap1 signaling pathway	1.487e-12	8.178e-11	227.44	6194.08
7	Ras signaling pathway	3.007e-12	9.698e-11	204.97	5437.89
8	Choline metabolism in cancer	6.296e-10	6.926e-9	213.95	4532.65
9	VEGF signaling pathway	1.415e-8	1.197e-7	241.64	4367.22
10	Fc epsilon RI signaling pathway	2.527e-8	1.985e-7	207.56	3631.06
11	Chemokine signaling pathway	1.472e-10	2.024e-9	159.71	3615.71
12	Thyroid cancer	6.931e-7	0.000003315	251.55	3567.44
13	Non-small cell lung cancer	3.189e-8	2.338e-7	195.31	3371.33
14	Glioma	3.764e-8	2.588e-7	187.03	3197.34
15	Bladder cancer	9.499e-7	0.000004267	225.02	3120.36
16	Lipid and atherosclerosis	2.915e-10	3.563e-9	141.97	3117.05
17	ErbB signaling pathway	6.256e-8	4.048e-7	163.86	2717.97
18	Phospholipase D signaling pathway	5.071e-9	4.648e-8	138.79	2650.86
19	AGE-RAGE signaling pathway in diabetic complications	1.207e-7	7.377e-7	138.15	2200.74
20	MAPK signaling pathway	1.916e-9	1.916e-8	102.61	2059.76
21	Endometrial cancer	0.000002737	0.00001004	155.34	1989.64
22	Long-term depression	0.000003034	0.00001043	149.87	1904.21
23	Growth hormone synthesis, secretion and action	2.434e-7	0.000001409	115.22	1754.62
24	GnRH secretion	0.000003690	0.00001230	140.02	1751.57
25	Thyroid hormone signaling pathway	2.602e-7	0.000001431	113.24	1716.86
26	Acute myeloid leukemia	0.000004240	0.00001372	133.43	1650.70
27	Mitophagy	0.000004434	0.00001394	131.37	1619.33
28	Central carbon metabolism in cancer	0.000004841	0.00001439	127.44	1559.65
29	Prolactin signaling pathway	0.000004841	0.00001439	127.44	1559.65
30	Natural killer cell mediated cytotoxicity	3.580e-7	0.000001875	104.27	1547.61
31	Melanoma	0.000005272	0.00001526	123.73	1503.75
32	Autophagy	4.285e-7	0.000002143	99.53	1459.45
33	Chronic myeloid leukemia	0.000006207	0.00001751	116.93	1401.96
34	B cell receptor signaling pathway	0.000007524	0.00002069	109.41	1290.72
35	Colorectal cancer	0.000009013	0.00002418	102.79	1194.10
36	Gap junction	0.000009659	0.00002530	100.36	1158.94
37	Hepatocellular carcinoma	9.698e-7	0.000004267	80.59	1115.92
38	GnRH signaling pathway	0.00001141	0.00002852	94.76	1078.51
39	Prostate cancer	0.00001295	0.00003165	90.71	1020.92
40	Axon guidance	0.000001335	0.000005648	74.20	1003.71
41	Melanogenesis	0.00001462	0.00003496	86.99	968.49
42	Longevity regulating pathway	0.00001506	0.00003524	86.11	956.11
43	C-type lectin receptor signaling pathway	0.00001596	0.00003658	84.39	932.17
44	Kaposi sarcoma-associated herpesvirus infection	0.000001687	0.000006872	69.84	928.42
45	Proteoglycans in cancer	0.000002145	0.000008426	65.64	856.70
46	Serotonergic synapse	0.00002047	0.00004504	77.45	836.23
47	Cholinergic synapse	0.00002047	0.00004504	77.45	836.23
48	Leukocyte transendothelial migration	0.00002102	0.00004534	76.75	826.63
49	Human immunodeficiency virus 1 infection	0.000002451	0.000009299	63.40	819.10
50	Sphingolipid signaling pathway	0.00002391	0.00005057	73.43	781.36
51	Platelet activation	0.00002704	0.00005612	70.37	740.21
52	Relaxin signaling pathway	0.00003043	0.00006199	67.56	702.67
53	FoxO signaling pathway	0.00003187	0.00006373	66.50	688.56
54	Apelin signaling pathway	0.00003643	0.00006909	63.51	649.04
55	Estrogen signaling pathway	0.00003643	0.00006909	63.51	649.04
56	Insulin signaling pathway	0.00003643	0.00006909	63.51	649.04
57	Apoptosis	0.00004054	0.00007559	61.21	618.98
58	Signaling pathways regulating pluripotency of stem cells	0.00004140	0.00007590	60.77	613.26
59	Breast cancer	0.00004495	0.00008106	59.07	591.24
60	Gastric cancer	0.00004680	0.00008303	58.25	580.74
61	mTOR signaling pathway	0.00005163	0.00008875	56.31	555.83
62	Oxytocin signaling pathway	0.00005163	0.00008875	56.31	555.83
63	Cellular senescence	0.00005366	0.00009081	55.57	546.37
64	Hepatitis C	0.00005469	0.00009115	55.20	541.75
65	Hepatitis B	0.00006004	0.00009712	53.45	519.59
66	MicroRNAs in cancer	0.00001104	0.00002825	42.88	489.47
67	Pathways in cancer	0.000002922	0.00001037	37.00	471.55
68	Alcoholism	0.00009052	0.0001443	46.39	431.86
69	Focal adhesion	0.0001139	0.0001790	42.84	388.99
70	Th1 and Th2 cell differentiation	0.0009195	0.001264	55.28	386.48
71	Viral carcinogenesis	0.0001173	0.0001817	42.41	383.81
72	Phosphatidylinositol signaling system	0.001021	0.001387	52.36	360.55
73	Inflammatory mediator regulation of TRP channels	0.001042	0.001398	51.81	355.72
74	Regulation of actin cytoskeleton	0.0001449	0.0002212	39.42	348.45
75	Human T-cell leukemia virus 1 infection	0.0001468	0.0002212	39.23	346.29
76	Pancreatic secretion	0.001128	0.001496	49.73	337.48
77	Human cytomegalovirus infection	0.0001590	0.0002364	38.16	333.78
78	NF-kappa B signaling pathway	0.001173	0.001536	48.75	328.95
79	Thermogenesis	0.0001741	0.0002553	36.98	320.12
80	Th17 cell differentiation	0.001241	0.001606	47.35	316.84
81	Chemical carcinogenesis	0.0001901	0.0002751	35.87	307.37
82	Pathways of neurodegeneration	0.00005889	0.00009668	27.63	269.09
83	Aldosterone-regulated sodium reabsorption	0.01835	0.02268	61.59	246.23
84	Human papillomavirus infection	0.0004945	0.0007064	25.69	195.56
85	Cushing syndrome	0.002578	0.003297	32.41	193.21
86	PI3K-Akt signaling pathway	0.0006016	0.0008484	23.98	177.83
87	Alzheimer disease	0.0006789	0.0009452	22.98	167.63
88	Vibrio cholerae infection	0.02473	0.03022	45.22	167.30
89	Glycerolipid metabolism	0.03009	0.03637	36.91	129.31
90	cAMP signaling pathway	0.004935	0.006239	23.10	122.71
91	Adipocytokine signaling pathway	0.03398	0.04062	32.55	110.09
92	Epithelial cell signaling in Helicobacter pylori infection	0.03446	0.04076	32.08	108.04
93	Shigellosis	0.006353	0.007941	20.23	102.35
94	Inositol phosphate metabolism	0.03591	0.04203	30.74	102.25
95	Pancreatic cancer	0.03736	0.04326	29.50	96.98
96	Fc gamma R-mediated phagocytosis	0.04747	0.05437	23.03	70.18
97	Glycerophospholipid metabolism	0.04794	0.05437	22.79	69.22
98	Progesterone-mediated oocyte maturation	0.04890	0.05489	22.32	67.37
99	Insulin resistance	0.05272	0.05851	20.65	60.76
100	HIF-1 signaling pathway	0.05319	0.05851	20.45	60.01
101	Vascular smooth muscle contraction	0.06456	0.07031	16.72	45.80
102	Yersinia infection	0.06644	0.07165	16.22	43.98
103	JAK-STAT signaling pathway	0.07813	0.08344	13.68	34.89
104	Tight junction	0.08138	0.08607	13.11	32.89
105	Neutrophil extracellular trap formation	0.09060	0.09491	11.70	28.10
106	Coronavirus disease	0.1102	0.1143	9.50	20.97
107	Calcium signaling pathway	0.1137	0.1169	9.18	19.96
108	Salmonella infection	0.1178	0.1189	8.84	18.92
109	Parkinson disease	0.1178	0.1189	8.84	18.92
110	Endocytosis	0.1191	0.1191	8.74	18.59

CategoryUncategorized

Autoimmunity- Anti-thyroid peroxidase antibody positivity

Anti-thyroid peroxidase antibody positivity-GO