Tachypnea (HP:0002789)
Very rapid breathing.
Synonyms: Increased respiratory rate or depth of breathing, Polypnea
Comment: In adults, a beathing rate of between 12-20 breaths per minute is normal and tachypnea is present with a ventilatory rate greater than 20 breaths per minute.
Cross References: MSH:D059246, SNOMEDCT_US:271823003, UMLS:C0231835
GO: Biological Process
| Index | Name | P-value | Adjusted p-value | Odds Ratio | Combined score |
| 1 | cilium assembly (GO:0060271) | 7.884e-19 | 2.129e-17 | 196860.00 | 8205971.98 |
| 2 | ciliary basal body-plasma membrane docking (GO:0097711) | 8.554e-18 | 1.155e-16 | 915.08 | 35962.78 |
| 3 | cilium organization (GO:0044782) | 2.747e-17 | 2.472e-16 | 812.51 | 30983.64 |
| 4 | plasma membrane bounded cell projection assembly (GO:0120031) | 1.681e-16 | 1.135e-15 | 659.81 | 23965.68 |
| 5 | smoothened signaling pathway (GO:0007224) | 3.049e-12 | 1.372e-11 | 665.33 | 17642.09 |
GO: Cellular Component
| Index | Name | P-value | Adjusted p-value | Odds Ratio | Combined score |
| 1 | cilium (GO:0005929) | 3.495e-12 | 2.447e-11 | 200.46 | 5288.15 |
| 2 | ciliary membrane (GO:0060170) | 4.016e-7 | 0.000001406 | 305.54 | 4499.94 |
| 3 | cell projection membrane (GO:0031253) | 0.00001104 | 0.00002576 | 95.83 | 1093.80 |
| 4 | bounding membrane of organelle (GO:0098588) | 0.005508 | 0.009639 | 10.78 | 56.10 |
| 5 | cell-cell junction (GO:0005911) | 0.1276 | 0.1786 | 8.12 | 16.71 |
Hub genes predicted as biomarkers & predicted FDA approved drugs
| Hub Genes (ranked) | FDA-Approved Drugs |
| TMEM231 | – |
| TMEM138 | – |
| B9D1 | – |
| CC2D2A | – |
| CEP41 | – |
| TCTN3 | – |
| TCTN2 | – |
| RPGRIP1L | – |
| MKS1 | – |
| TMEM216 | – |
