Autoimmunity-Lymphopenia
May 23, 2022HPO Term: Lymphopenia (HP:0001888)
Definition: A reduced number of lymphocytes in the blood
Synonyms: Absolute lymphocyte count decrease; Low lymphocyte number; Decreased blood lymphocyte number; Lymphocytopenia
Plain-language label: Low lymphocyte count
Plain-language definition: A decreased number of lymphocytes (a type of white blood cell) in the blood.
Gene- Association
GO
Hub Genes & FDA Drug repurposing
CD19 | BLINATUMOMAB |
CTLA4 | IPILIMUMAB, ABATACEPT |
ZAP70 | – |
CD3E | MUROMMONAB-CD3, CATUMAXOMAB, BLINATUMOMAB |
RAG1 | – |
RAG2 | – |
CD3D | MUROMMONAB-CD3, CATUMAXOMAB, BLINATUMOMAB |
IL2RA | BASILIXIMAB, DACLIZUMAB, ALDESLEUKIN, DENILEUKIN DIFTITOX, CETIRIZINE |
CD3G | MUROMMONAB-CD3, CATUMAXOMAB, BLINATUMOMAB |
IKZF1 | LENALIDOMIDE |